|
rs2569190
|
CD14;TMCO6
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs2569190
|
CD14;TMCO6
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs5744455
|
CD14;TMCO6
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs5744455
|
CD14;TMCO6
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation |
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs2569190
|
CD14;TMCO6
|
Periodontitis
|
|
0.030 |
GeneticVariation |
BEFREE |
Thus, the aim of this study was to evaluate the influence of the <i>TLR4</i> A896G (rs4986790), <i>TLR4</i> C1196T (rs4986791), <i>CD14</i> C-260T (rs2569190), <i>RANKL</i> (<i>TNFSF11</i>, rs2277438), and <i>OPG</i> (<i>TNFSF11B</i> C163T, rs3102735) polymorphisms in periodontitis.
|
31281226 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
The SNP rs2569190 significantly contribute to susceptibility and development of cardiovascular disease, particularly in the East Asian population and in the subtype CHD group, in addition, a potential association was observed in the AMI group, T allele acts as a risk factor for cardiovascular disease.
|
30922395 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation |
BEFREE |
Numerous published studies have investigated the relationship between the CD14-260C>T (rs2569190) polymorphism and the risk of myocardial infarction (MI).
|
31183977 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Anemia, Sickle Cell
|
|
0.010 |
GeneticVariation |
BEFREE |
The CD14 (rs2569190) gene promoter demonstrated a significant difference (p < 0.02) between African and African American SCD groups, with the mutant variant (-159 T/T) more frequent (p < 0.0002) in African American SCD (38.9% versus 26.2%).
|
31474499 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Ischemic stroke
|
|
0.010 |
GeneticVariation |
BEFREE |
The current evidence indicated that <i>CD14</i> rs2569190 C>T polymorphism was not a critical risk factor for IS development.
|
30613146 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
IgE-mediated food allergy
|
|
0.010 |
GeneticVariation |
BEFREE |
Development of FA was associated with longer periods of breastfeeding (adjusted OR = 1.792, P = .03), and this dietary pattern was more significantly related to the development of FA in infants with the homozygous TT genotype of CD14 (rs2569190) and more than 1 copy of GSTM1 and GSTT1.
|
30930272 |
2019 |
|
rs2563298
|
CD14;TMCO6
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2563298
|
CD14;TMCO6
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of COL4A1 (rs605143, rs565470) and CD14 (rs2569190) genes polymorphism with coronary artery disease.
|
29299748 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Biliary Atresia
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of two cis-regulated variants in CD14 (rs2569190) and NOTCH2 (rs835576) with BA susceptibility, using the largest case-control cohort, totaling 506 BA patients and 1,473 healthy controls in a Southern Chinese population.
|
30439647 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Congenital atresia of extrahepatic bile duct
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of two cis-regulated variants in CD14 (rs2569190) and NOTCH2 (rs835576) with BA susceptibility, using the largest case-control cohort, totaling 506 BA patients and 1,473 healthy controls in a Southern Chinese population.
|
30439647 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Acute myocardial infarction
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the possible association between CD14 C(-260)T (rs2569190) gene polymorphism and the risk of acute myocardial infarction in the Egyptian population.
|
29874995 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of COL4A1 (rs605143, rs565470) and CD14 (rs2569190) genes polymorphism with coronary artery disease.
|
29299748 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Allergic rhinitis (disorder)
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the accumulating evidence does not support an association of IL-13 SNP rs1800925 and CD14 SNP rs2569190 with AR risk.
|
29687183 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, CD14 (rs2569190), CC (P = 0.008) genotypes, and C allele (P = 0.007) were found to be a positive risk factor, while TT genotype (P = 0.045) and T allele (P = 0.007) as negative risk factor for CAD.
|
29299748 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In genetic model analysis, the allele model, recessive model, and homozygous model of rs2569190 and rs2915863 embodied strong correlations with GD after the adjusting of age and gender (<i>P</i> = 0.014, <i>P</i> = 0.015, <i>P</i> = 0.009, and <i>P</i> = 0.014, <i>P</i> = 0.001, <i>P</i> = 0.006, respectively).
|
30700980 |
2018 |
|
rs2569192
|
CD14;TMCO6
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2569192
|
CD14;TMCO6
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2915863
|
CD14;TMCO6
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In genetic model analysis, the allele model, recessive model, and homozygous model of rs2569190 and rs2915863 embodied strong correlations with GD after the adjusting of age and gender (<i>P</i> = 0.014, <i>P</i> = 0.015, <i>P</i> = 0.009, and <i>P</i> = 0.014, <i>P</i> = 0.001, <i>P</i> = 0.006, respectively).
|
30700980 |
2018 |
|
rs5744454
|
CD14;TMCO6
|
Complicated malaria
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data not only reinstates that CD14 of TLR pathway plays a predominant role in P. falciparum malaria, it establishes a functional basis for genetic association of rs5744454 with P. falciparum severe malaria by demonstrating a cis-regulatory role of this promoter polymorphism.
|
30337251 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Periodontitis
|
|
0.030 |
GeneticVariation |
BEFREE |
The genetic variation in the CD14 rs2569190 promoter region contributes to the susceptibility of developing periodontitis.
|
28829191 |
2017 |